Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study
نویسندگان
چکیده
AIM To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwanese military male cohort. METHODS We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study. Cases of chronic hepatitis B (n = 121) were defined by personal history and positive detection of hepatitis B surface antigen. Cases of nonalcoholic steatohepatitis (n = 129) were defined by alanine transaminase level > 60 U/L, liver ultrasound finding of steatosis, and absence of viral hepatitis A, B or C infection. All other study participants were defined as unaffected (n = 3419). Physical fitness was evaluated by performance in 3000-m run, 2-min sit-ups, and 2-min push-ups exercises, with all the procedures standardized by a computerized scoring system. Multiple linear regression analysis was used to determine the relationship. RESULTS Chronic hepatitis B negatively correlated with 2-min push-up numbers (β = -2.49, P = 0.019) after adjusting for age, service specialty, body mass index, systolic and diastolic blood pressures, current cigarette smoking, alcohol intake status, serum hemoglobin, and average weekly exercise times. Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time (β = 11.96, P = 0.084) and negatively correlated with 2-min sit-up numbers (β = -1.47, P = 0.040). CONCLUSION Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males, and future study should determine the underlying mechanism.
منابع مشابه
The diagnostic value of contrast-enhanced ultrasound in the management of HCC
Introduction Hepatocellular carcinoma (HCC) is one of the most common gastrointestinal tumors and the third leading cause of cancer mortality [1]. Chronic hepatitis B and C, alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH) play a major role in the development of HCC. To reduce the mortality associated with HCC, early detection and initiation of curative therapy are essent...
متن کاملThe Effect of Diet and Exercise on Improvement of Quality of Life in Patients with Nonalcoholic Steatohepatitis
Background & Aims: Nonalcoholic steatohepatitis (NASH) is part of nonalcoholic fatty liver disease (NAFLD). No special medical treatment is known for this disease, and lifestyle modification is the best known method of treatment. We aimed to compare the effect of diet and aerobic exercise with that of diet alone on the quality of life of patients with NASH. Methods: In the present study, 25 pat...
متن کاملHiV and Liver disease
Fig. 1: Potential causes of liver enzyme elevations in HIV-infected patients. HBV, hepatitis B virus; HCV, hepatitis C virus; NASH, nonalcoholic steatohepatitis. Alcohol Drugs Medications HCV or HBV Chronic Hepatitis Drug-related Hepatotoxicity HIV HAART Other Liver Diseases: NASH*
متن کاملEighty percent of hepatocellular carcinoma cases are caused by infection with hepatitis B virus (HBV) or hepatitis C virus (HCV). Cases of fatty liver and nonalcoholic steatohepatitis (NASH)
متن کامل
Noninvasive markers of fibrosis and inflammation in clinical practice: prospective comparison with liver biopsy.
BACKGROUND The efficiency of transient elastography for the assessment of liver fibrosis has been evaluated mainly in patients with chronic hepatitis C and chronic hepatitis B, with few studies with nonviral chronic liver disease (CLD) such as autoimmune hepatitis, alcoholic liver disease and nonalcoholic steatohepatitis. In this study, we examined the value of transient elastography in a numbe...
متن کامل